2026

• Medium-Sized-Molecule Encapsulation in Coordination Cages via Solid-State Mechanochemistry
  K. Iizuka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2026, 148, 4588–4598. [ 10.1021/jacs.5c20185 ]
• Monomer Isolation from Oligomeric Proteins within Coordination Cages to Study Interface Ligand Binding
  R. Ebihara, T. Nakama, K. Morishima, M. Yagi-Utsumi, M. Sugiyama, M. Fujita
  J. Am. Chem. Soc. 2026, 148, 1872–1880. [ 10.1021/jacs.5c19487 ]

2025

• Enzyme Immobilization in Porous Crystals via Cage Encapsulation
  H.-K. Liu, T. Nakama, S. Funami, R. Ebihara, T. Mitsuhashi, M. Fujita
  Angew. Chem. Int. Ed. 2025, 64, e202517027. [ 10.1002/anie.202517027 ]
• Engineering β-sheet morphologies via metal cross-linking and side chain modifications
  E. Tsunekawa, T. Nakama, M. Fujita, T. Sawada
  Chem. Sci. 2025, 16, 18832–18837. [ 10.1039/D5SC05237H ]
• Discovery of a New Type of Terpene Synthase Coded by an Orphan Gene in a Giant Virus
  C. Park, S. Tsutsumi, T. Mitsuhashi, M. Fujita
  Biochemistry 2025, 64, 3866–3871. [ 10.1021/acs.biochem.5c00354 ]
• A Visible-Light-Responsive Octahedral Cage for Efficient and Selective Cross-[2+2] Cycloadditions
  R. Tanaka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2025, 147, 25142–25147. [ 10.1021/jacs.5c07355 ]
• Micro Crystalline Sponge Method Combined with Small-Wedge Synchrotron Crystallography for Nanogram Scale Molecular Structure Elucidation
  S. Yoshida, S. Baba, N. Mizuno, Y. Nakamura, S. Sato, M. Fujita
  J. Am. Chem. Soc. 2025, 147, 23917–23922. [ 10.1021/jacs.5c06360 ]
• Proximity-induced saccharide binding to a protein's active site within a confined cavity of coordination cages
  T. Nakama, M. Tadokoro, R. Ebihara, M. Yagi-Utsumi, K. Kato, M. Fujita
  Chem. Sci. 2025, 16, 10549-10554. [ 10.1039/D5SC00782H ]
• An M60L60 metal-peptide capsid with a 60-crossing woven network
  Y. Inomata, S. Oguma, N. Sagara, A. Nishijima, Y. Saburomaru, S. Yoshida, T. Kajitani, K. Shimokawa, S. Sato, M. Yoshizawa, M. Fujita, T. Sawada
  Chem 2025, 11, 102555. [ 10.1016/j.chempr.2025.102555 ]
• Self-Assembly of Silver Nanoclusters by Cooperative Acetylene Bonding with Mutual Pyridyl Coordination
  T. Tsurumi, T. Nakagawa, T. Kikuchi, K. Adachi, H. Hayashi, A. Takai, T. Kaneko, T. Uruga, D. Hashizume, Y. Nakamura, M. Fujita, Y. Domoto
  ChemistryEurope 2025, 3, e202500069. [ 10.1002/ceur.202500069 ]
• Step-by-Step Self-Assembly of a Double-Walled Knotted Cage with Increasing Topological Complexity
  H. Takezawa, Y. Tamura, M. Fujita
  Chem. Eur. J. 2025, 21, e202500009. [ 10.1002/chem.202500009 ]
• Helical Sense Control of Metal–Peptide Torus Frameworks Leading to the Folding and Assembly of a Ag21L14 Braided Peptide Nanotube
  S. Oguma, Y. Inomata, A. Hayakawa, T. Nakama, M. Fujita, T. Sawada
  J. Am. Chem. Soc. 2025, 147, 9098–9102. [ 10.1021/jacs.5c01458 ]
• Host-Guest Chemistry in a Capillary Applied to the Facilitation of the Crystalline Sponge Method
  W. He, H. Takezawa, R. Yakushiji, S. Yoshida, S. Sato, M. Fujita
  Angew. Chem. Int. Ed. 2025, 64, e202501025. [ 10.1002/anie.202501025 ]
• Supramolecular coordination cages as crystalline sponges through a symmetry mismatch strategy
  W. He, Y. Yu, K. Iizuka, H. Takezawa, M. Fujita
  Nat. Chem. 2025, 17, 653–662. [ 10.1038/s41557-025-01750-x ]
• Host‐in‐Host Complexation: Activating Classical Hosts through Complete Encapsulation within an M9L6 Coordination Cage
  K. Iizuka, H. Takezawa, M. Fujita
  Angew. Chem. Int. Ed. 2025, 64, e202422143. [ 10.1002/anie.202422143 ]
• Fine-Tuning of the Sequential Self-Assembly of Entangled Polyhedra by Exploiting the Side-Chain Effect
  Y. Domoto, R. Nakabayashi, T. Tsurumi, K. Yamamoto, H. Hayashi, Y. Nakamura, M. Fujita
  Chem. Asian. J. 2025, 20, e202401378. [ 10.1002/asia.202401378 ]
• Physical Isolation of Single Protein Molecules within Well-Defined Coordination Cages to Enhance Their Stability
  R. Ebihara, T. Nakama, K. Morishima, M. Yagi-Utsumi, M. Sugiyama, D. Fujita, S. Sato, M. Fujita
  Angew. Chem. Int. Ed. 2025, 64, e202419476. [ 10.1002/anie.202419476 ]
• A Discrete Four-Stranded β-Sheet through Catenation of M2L2 Metal–Peptide Rings
  E. Tsunekawa, M. Fujita, T. Sawada
  Angew. Chem. Int. Ed. 2025, 64, e202416442. [ 10.1002/anie.202416442 ]

2024

• Template and Solid-State Assisted Assembly of an M9L6 Expanded Coordination Cage for Medium-Sized-Molecule Encapsulation
  K. Iizuka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2024, 146, 32311–32316. [ 10.1021/jacs.4c14509 ]
• New workflow for the structure elucidation of trace amount natural products with microgram-scale crystalline sponge method: a scaled-down genome-mining study
  C. Park, T. Mitsuhashi, N. Wada, T. Kikuchi, M. Fujita
  Chem. Lett. 2024, 53, upae202. [ 10.1093/chemle/upae202 ]
• Organic solvent-induced structural changes in a protein confined in a giant coordination cage
  H. Tamura, T. Nakama, A. Rossen, H. Ishikita, M. Fujita
  Chem. Lett. 2024, 53, upae101. [ 10.1093/chemle/upae101 ]
• Conformational Analysis of (+)-Germacrene D-4-ol Using the Crystalline Sponge Method to Elucidate the Origin of its Instability
  Y. Jung, T. Mitsuhashi, K. Kageyama, T. Kikuchi, S. Sato, M. Fujita
  Chem. Eur. J. 2024, 39, e202400512. [ 10.1002/chem.202400512 ]
• Functional Plasticity of a Viral Terpene Synthase, OILTS, that Shows Non–Specific Metal Cofactor Binding and Metal–dependent Biosynthesis
  Y. Jung, T. Mitsuhashi, T. Kikuchi, M. Fujita
  Chem. Eur. J. 2024, 30, e202304317. [ 10.1002/chem.202304317 ]
• Selective Synthesis and Functionalization of an Acyclic Methylene-Bridged-Arene Trimer in a Cage
  H. Takezawa, K. Iizuka, M. Fujita
  Angew. Chem. Int. Ed. 2024, 63, e202319140. [ 10.1002/anie.202319140 ]
• Rapid Analysis of Trace Amounts of Amino Acid Derivatives by a Formyl Group-Installed Crystalline Sponge
  B. Zhou, S. Utjapimuk, K. Yan, R. Dubey, T. Kikuchi, T. Mitsuhashi, M. Fujita
  Chem. Asian. J. 2024, 19, e202300969. [ 10.1002/asia.202300969 ]

2023

• Function and Structure of a Terpene Synthase Encoded in a Giant Virus Genome
  Y. Jung, T. Mitsuhashi, S. Sato, M. Senda, T. Senda, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 25966–25970. [ 10.1021/jacs.3c10603 ]
• Chemical Site-Differentiation of Calix[4]arenes through Enforced Conformations by Confinement in a Cage
  K. Iizuka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 25971–25975. [ 10.1021/jacs.3c10720 ]
• Tetradehydro-Diels-Alder Reactions of Flexible Arylalkynes via Folding Inside a Molecular Cage
  G. R. Genov, H. Takezawa, H. Hayakawa, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 17013–17017. [ 10.1021/jacs.3c06301 ]
• X-ray and Electron Diffraction Observations of Steric Zipper Interactions in Metal-Induced Peptide Cross-β Nanostructures
  E. Tsunekawa, Y. Otsubo, Y. Yamada, A. Ikeda, N. Adachi, M. Kawasaki, A. Takasu, S. Aramaki, T. Senda, S. Sato, S. Yoshida, M. Fujita, T. Sawada
  J. Am. Chem. Soc. 2023, 145, 16160–16165. [ 10.1021/jacs.3c04710 ]
• Synthetic Modulation of an Unstable Dehydrosecodine-type Intermediate and Its Encapsulation into a Confined Cavity Enable Its X-ray Crystallographic Observation
  G. Tay, T. Wayama, H. Takezawa, S. Yoshida, S. Sato, M. Fujita, H. Oguri
  Angew. Chem. Int. Ed. 2023, 62, e202305122. [ 10.1002/anie.202305122 ]
• Interconversion of Highly Entangled Polyhedra into Concave Polyhedra by Nitrate-Induced Ternary Coordination
  Y. Domoto, M. Abe, G. R. Genov, Z. Yu, M. Fujita
  Angew. Chem. Int. Ed. 2023, 62, e202303714. [ 10.1002/anie.202303714 ]
• Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages
  T. Nakama, A. Rossen, R. Ebihara, M. Yagi-Utsumi, D. Fujita, K. Kato, S. Sato, M. Fujita
  Chem. Sci. 2023, 14, 2910–2914. [ 10.1039/D2SC05879K ]